https://journalajob.com/index.php/AJOB <p style="text-align: justify;">The aim of <strong>Asian Journal of Biology (ISSN: 2456-7124)</strong> is to publish high quality papers (<a href="https://journalajob.com/index.php/AJOB/general-guideline-for-authors">Click here for Types of paper</a>) with broad areas of Aerobiology, Agriculture, Anatomy, Astrobiology, Biochemistry, Bioengineering, Bioinformatics, Biomathematics or Mathematical Biology, Biomechanics, Biomedical research, Biophysics, Biotechnology, Building biology, Botany, Cell biology, Conservation Biology, Cryobiology, Developmental biology, Food biology, Ecology, Embryology, Entomology, Environmental Biology, Epidemiology, Ethology, Evolutionary Biology, Genetics, Herpetology, Histology, Ichthyology, Integrative biology, Limnology, Mammalogy, Marine Biology, Microbiology, Molecular Biology, Mycology, Neurobiology, Oceanography, Oncology, Ornithology, Population biology, Population ecology, Population genetics, Paleontology, Pathobiology or pathology, Parasitology, Pharmacology, Physiology, Psychobiology, Sociobiology, Structural biology, Virology and Zoology. By not excluding papers based on novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer-reviewed, open-access INTERNATIONAL journal.</p> <p style="text-align: justify;"><strong>NAAS Score: 4.52 (2026) </strong></p> en-US [email protected] (Asian Journal of Biology) [email protected] (Asian Journal of Biology) Wed, 09 Sep 2026 07:21:47 +0000 OJS 3.3.0.21 http://blogs.law.harvard.edu/tech/rss 60 https://journalajob.com/index.php/AJOB/article/view/695 <p><strong>Background:</strong> <em>Erythrina crista-galli</em> is a medicinal plant containing bioactive constituents of potential biological importance. Evaluation of its radical-scavenging activity and interaction with red blood cells is important for characterising the antioxidant activity and haemolytic potential of its leaf extract.</p> <p><strong>Aim:</strong> The present study aims to investigate the antioxidant activity and haemolytic potential of the methanol leaf extract of <em>Erythrina crista-galli.</em></p> <p><strong>Method:</strong> Anti-radical activity was assessed using the DPPH and ABTS radical scavenging assays, and the haemolytic activity of the methanol leaf extract was evaluated.</p> <p><strong>Results:</strong> The methanol leaf extract of <em>E. crista-galli </em>demonstrated DPPH scavenging activity; at extract concentrations of 6.25, 12.5, 25, 50, and 75 µg/mL, the recorded inhibition values were 3.125%, 15.625%, 25.0%, 31.25%, and 37.5%, showing a gradual enhancement in antioxidant potential with increasing concentration. The percentage inhibition of ABTS radicals increased progressively with increasing extract concentration, indicating a concentration-dependent antioxidant effect. Quercetin was used as the standard. The plant extract exhibited a concentration-dependent increase in haemolytic activity.</p> <p><strong>Conclusion:</strong> The present findings confirm the existence of mild and remarkable antioxidant activity and significant haemolytic potential in the leaf extract of <em>E. crista-galli</em>, and these data could pave the way for further research.</p> Keerthana H. Deshpande, Syed Muskan Imran, B. S. Ramesh Copyright (c) 2026 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://journalajob.com/index.php/AJOB/article/view/695 Wed, 09 Sep 2026 00:00:00 +0000 https://journalajob.com/index.php/AJOB/article/view/696 <p><strong>Background: </strong>Type 2 diabetes mellitus (T2DM) is characterised by chronic hyperglycaemia and persistent low-grade inflammation, which contribute to disease progression and the development of vascular complications. Alterations in inflammatory cytokines and haematopoietic factors have been implicated in the pathogenesis of T2DM and may provide valuable insights into disease-associated immune and erythropoietic responses.</p> <p><strong>Aim: </strong>This study evaluated haematopoietic and inflammatory cytokine profiles in patients with type 2 diabetes mellitus in Enugu, Nigeria.</p> <p><strong>Methods: </strong>A cross-sectional study was conducted involving 86 patients with T2DM and 58 apparently healthy controls. Fasting blood glucose (FBG), glycated haemoglobin (HbA1c), complete blood count, interleukin-1 beta (IL-1β), interleukin-10 (IL-10), and erythropoietin (EPO) concentrations were determined using standard laboratory methods. Data were analysed using one-way analysis of variance, with statistical significance set at p &lt; 0.05.</p> <p><strong>Results: </strong>Patients with T2DM exhibited significantly higher FBG and HbA1c levels compared with controls (p &lt; 0.001), indicating poor glycaemic control. Interleukin-1β concentrations were significantly elevated in diabetic males (14.36 ± 0.99 pg/mL) and females (17.17 ± 0.66 pg/mL) compared with their respective controls (p &lt; 0.05). In contrast, IL-10 levels were markedly reduced in diabetic males (3.44 ± 0.28 pg/mL) and females (3.70 ± 0.21 pg/mL) relative to controls (p &lt; 0.001). Erythropoietin concentrations were significantly increased in diabetic males (31.50 ± 1.09 mU/mL; p &lt; 0.001) and diabetic females (28.63 ± 1.62 mU/mL; p &lt; 0.05) compared with controls. Total white blood cell and neutrophil counts were also significantly elevated, particularly among diabetic females, reflecting enhanced systemic inflammatory activity.</p> <p><strong>Conclusion: </strong>Type 2 diabetes mellitus is associated with significant alterations in inflammatory cytokines and haematopoietic activity, characterised by elevated IL-1β, reduced IL-10, increased erythropoietin concentrations, and leukocyte abnormalities. These findings highlight the presence of persistent inflammation and altered haematopoietic responses in T2DM and suggest that inflammatory and haematopoietic biomarkers may serve as useful indicators of disease progression and metabolic dysfunction.</p> Ugwu G. Ndidiamaka, Ufelle S. Anayo, Victor O. Apeh., Emmanuel I. Eze, Benjamin O. Ezema Copyright (c) 2026 Author(s). The licensee is the journal publisher. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://journalajob.com/index.php/AJOB/article/view/696 Thu, 10 Sep 2026 00:00:00 +0000