Asian Journal of Biology <p style="text-align: justify;">The aim of <strong>Asian Journal of Biology&nbsp;(ISSN: 2456-7124)</strong>&nbsp;is to publish high quality papers (<a href="/index.php/AJOB/general-guideline-for-authors">Click here for Types of paper</a>) with broad areas of Aerobiology, &nbsp;Agriculture, Anatomy, Astrobiology, Biochemistry, Bioengineering, Bioinformatics, Biomathematics or Mathematical Biology, Biomechanics, Biomedical research, Biophysics, Biotechnology, Building biology, Botany, Cell biology, Conservation Biology, Cryobiology, Developmental biology, Food biology, Ecology, Embryology, Entomology, Environmental Biology, Epidemiology, Ethology, Evolutionary Biology, Genetics, Herpetology, Histology, Ichthyology, Integrative biology, Limnology,&nbsp; Mammalogy, Marine Biology, Microbiology, Molecular Biology, Mycology, Neurobiology, Oceanography, Oncology, Ornithology, Population biology, Population ecology, Population genetics, Paleontology, Pathobiology or pathology, Parasitology, Pharmacology, Physiology, Psychobiology, Sociobiology, Structural biology, Virology and&nbsp; Zoology. This is a quality controlled, peer-reviewed, open access INTERNATIONAL journal.</p> SCIENCEDOMAIN international en-US Asian Journal of Biology 2456-7124 Assessment of Genetic Diversity in Indian Spinach (Basella spp L) Accessions Using RAPD Markers <p><strong>Background:</strong> Indian spinach is one of the important underexploited tropical leafy vegetables which have high nutritional and medicinal value. Molecular marker technology has greatly accelerated the process involved in breeding programs for the improvement of various crops and its techniques have been considered to be the most suitable means of estimating genetic diversity.</p> <p><strong>Aim:</strong> The study is to determine the genetic diversity among the accessions of Indian spinach collected from South western Nigeria using molecular markers.</p> <p><strong>Methodology:</strong> Random amplified polymorphic DNA (RAPD) markers were used to assay 20 accessions of Indian spinach (<em>Basella spp</em>) collected from the south western states of Nigeria (Oyo, Osun, Ogun, Ondo and Ekiti).</p> <p><strong>Results: </strong>Results showed that RAPD markers were highly polymorphic and generated alleles ranging from two to eight. The polymorphic information content was highest for the OPT-17 primer (0.757) and the mean average was (4.23) Moreover, gene diversity (0.785) was high, and cluster analysis delineated the accessions into five groups, which indicated that a significant genetic diversity was present among the accessions studied. A dendrogram clustering method revealed five major clusters. Clusters I, II and IV had one accessions each, III had four and V had thirteen accessions.</p> <p><strong>Conclusion:</strong> The result revealed that RAPD markers are useful for genetic characterization as they provide information on the interspecific and phylogenetic statuses of the accessions. The markers also showed a genetic variability that could be exploited for varietal delineation and improvement of the vegetable in Nigeria.</p> Olalekan Ibrahim Sobowale Benjamin Oluwole Akinyele Alexander Chukwunweike Odiyi Adeyela Ibironke Okunlola Emmanuel Oluwakayode Ajayi Omolara Loveth Aderonmu ##submission.copyrightStatement## 2020-11-21 2020-11-21 1 8 10.9734/ajob/2020/v10i430111 Recent Research Progress and Current Understanding of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) <p>Coronaviruses (CoVs) are a large group of enveloped viruses with a positive-sense RNA that have characteristic spikes projecting from their surface. CoVs are well known for their large RNA genome (26-32 kb). They primarily affect mammals and birds, causing infections of the respiratory and gastrointestinal tracts. The emergence of human CoVs (HCoVs) has been reported once every ten years for the last three decades. The most recent emergence occurred in December 2019, when a new strain of CoVs named SARS-CoV-2 caused the coronavirus disease 2019 (COVID-19) pandemic, leaving a devastating impact on the global healthcare. The early cases were associated with the Huanan seafood market in Wuhan, although the exact origin of the virus is still being debated. Phylogenetic analysis reveals bats to be the reservoir hosts, but the intermediate host responsible for spill-over into the human population remains debatable. Accumulating evidence cites pangolins based on the similarity of receptor binding domain in spike protein; however, the search for a conclusive intermediate host that aided in the inter-species crossover is still underway. Advances have been made in our understanding of the functions of each structural protein, but certain non-structural proteins and accessory proteins are yet to be characterised. Owing to the large genetic diversity of CoVs that arise through recombination, genetic variation, or gene gains/losses, future re-emergence of CoVs are most likely.&nbsp; In this review, we provide an introduction to CoVs and discuss the origin, virology, genetics, phylogeny, and pathogenesis of SARS-CoV-2 based on relevant literature.</p> Shwetha Krishna Nandini Eswaran ##submission.copyrightStatement## 2020-11-25 2020-11-25 9 21 10.9734/ajob/2020/v10i430112